Antioxidant and anticholinesterase activities of Juglans Regıa L. growing in Turkey

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dc.contributor.authorKarakaya, Songül
dc.contributor.authorKoca, Mehmet
dc.contributor.authorYeşilyurt, Fatma
dc.contributor.authorHacımüftüoğlu, Ahmet
dc.contributor.authorIDhttps://orcid.org/0000-0002-3268-721Xtr_TR
dc.contributor.authorIDhttps://orcid.org/0000-0002-1517-5925tr_TR
dc.contributor.authorIDhttps://orcid.org/0000-0002-1336-6322tr_TR
dc.contributor.authorIDhttps://orcid.org/0000-0002-9658-3313tr_TR
dc.contributor.departmentEczacılık Fakültesitr_TR
dc.date.accessioned2020-04-02T06:37:15Z
dc.date.available2020-04-02T06:37:15Z
dc.date.issued2019
dc.description.abstractObjective: World's ageing population continues to grow older together with high percentage prevalence of Alzheimer's disease encourage science to find herbs or biologic compounds which can be utilized for it prophylaxis. Juglans regia L. is not simply an agricultural product, its fruits, leaves, barks, stems, pericarps, and flowers are all utilized for diversified medicinal usages. In the present investigation, we examined the anticholinesterase and antioxidant capacities of the lyophilized aqueous extracts of leaves from J. regia. Material and Method: Phenolic contents and antioxidant activity were assessed by Folin-Ciocalteu's, qualitative/quantitative DPPH and TBA methods. Anticholinesterase activity was assessed by Ellman’s method. Result and Discussion: The total phenolic content was found 478.32 mg/g. The extract indicated antioxidant activity with DPPH test (IC50: 123.66 μg/mL) and TBA assay (IC50: 209.23 μg/mL). Moreover, the extract of J. regia indicated remarkable inhibition towards acetylcholinesterase (40.09%) and butyrylcholinesyterase (56.23%) enzymes. These data propose that J. regia can be utilised a potency for pharmaceutical products which get antioxidant and anticholinesterase activity.tr_TR
dc.identifier.endpage238tr_TR
dc.identifier.issn/e-issn1015-3918
dc.identifier.issue03tr_TR
dc.identifier.startpage230tr_TR
dc.identifier.urihttps://doi.org/10.33483/jfpau.530099tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/70876
dc.identifier.volume43tr_TR
dc.language.isoentr_TR
dc.publisherAnkara : Ankara Üniversitesitr_TR
dc.relation.isversionof10.33483/jfpau.530099tr_TR
dc.relation.journalAnkara Üniversitesi Eczacılık Fakültesi Dergisitr_TR
dc.relation.publicationcategoryMakale - Ulusal - Editör Denetimli Dergi - Başka Kurum Yazarıtr_TR
dc.subjectAntioxidanttr_TR
dc.subjectAnticholinesterasetr_TR
dc.subjectJuglans regiatr_TR
dc.subjectJuglandaceaetr_TR
dc.titleAntioxidant and anticholinesterase activities of Juglans Regıa L. growing in Turkeytr_TR
dc.title.alternativeTürkiye'de yetişen Juglans Regıa L.’nın antioksidan ve antikolinesteraz aktiviteleritr_TR
dc.typeArticletr_TR

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Cilt:43 Sayı:03 (2019)