Electrochemical behaviorof biologically ımportantIndole derivatives
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Date
2011
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Abstract
Voltammetric techniques are most suitable to investigate the redox properties of a new drug. Use of electrochemistry is an important approach in drug discovery and research as well as quality control, drug stability, and determination of physiological activity. The indole nucleus is an essential element of a number of natural and synthetic products with significant biological activity. Indole derivatives are the well-known electroactive compounds that are readily oxidized at carbon-based electrodes, and thus analytical procedures, such as electrochemical detection and voltammetry, have been developed for the determination of biologicallyimportantindoles.Thispaper explainssomeoftherelevantandrecent achievementsintheelectrochemistry processes and parameters mainlyrelated to biologically important indolederivatives in view of drug discovery and analysis.
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Keywords
Electrochemical behavior, Indole