Browsing by Author "Soydal, Çiğdem"
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Item 18F-NaF positive bone metastases of non 18F-FDG avid mucinous gastric cancer(Galenos, 2014-01-28) Soydal, Çiğdem; Özkan, Elgin; Küçük, Nuriye Özlem; Kır, Kemal Metin; Tıp FakültesiItem Ga-68 DOTATATE accumulation in sarcoidosis(Cosmos Scholars, 2015-09-21) Soydal, Çiğdem; Küçük, Nuriye Özlem; Özkan, Elgin; Kumbasar, Özlem; Kır, Kemal Metin; Tıp FakültesiItem Intense Pituitary 18F-Fluorodeoxyglucose Positron Emission Tomography Uptake in a Patient with Diabetes Insipidus(2019) Soydal, Çiğdem; Nak, Demet; Tıp FakültesiItem Risk factors for predicting osteoporosis in patients who receive thyrotropin suppressive levothyroxine treatment for differentiated thyroid carcinoma(Galenos, 2019-05-29) Soydal, Çiğdem; Özkan, Elgin; Nak, Demet; Elhan, Atilla Halil; KÜçük, Nuriye Özlem; Kır, Kemal Metin; Tıp FakültesiObjectives: Endogenous hyperthyroidism accelerates bone turnover and shortens the normal bone remodeling cycle, which results in reduced bone density. It is estimated that suppressive levothyroxine (LT4) therapy also decreases bone density. The aim of this study was to define risk factors for osteoporosis development in patients under thyrotropin-stimulating hormone (TSH) suppressive treatment for differentiated thyroid cancer (DTC). Methods: Patients with a diagnosis of low or intermediate risk group DTC according to the American Thyroid Association 2015 guidelines and who have been receiving LT4 suppression therapy and were physically fit to undergo femur and lumbar vertebra bone density study were included in the study. Patients lacking information on demographic data, medical history, preoperative thyroid hormone status, or routine follow-up data were excluded from the study. A study form consisting of patient information on possible risk factors for osteoporosis such as gender, age, menopausal status, smoking, family history of osteoporosis, preoperative thyroid hormone status, postoperative hypoparathyroidism history, mean serum TSH levels, and duration of TSH suppression was created and filled out for each participant. Bone mineral densitometries of the femur and lumbar vertebrae were measured along with serum vitamin D and parathyroid hormone levels. Results: During TSH suppression (mean 7.2±4.5 years, range: 1-26), osteoporosis was detected in 89 (9.6%) patients. The mean time to develop osteoporosis was significantly different in patients with or without a family history of osteoporosis (15.3±0.4 versus 20.3±0.6 years; p=0.002). Similarly, the mean time to develop osteoporosis for was found to be significantly shorter in postmenopausal patients than that for premenopausal women (18.6±0.7 versus 20.4±0.4 years; p<0.001). Male gender (p<0.001), a family history of osteoporosis (p=0.001) and menopausal state (p<0.001) were identified as independent predictive factors for developing osteoporosis. Conclusion: Postmenopausal women, men, and patients with a family history who receive TSH-suppression treatment have a tendency to develop osteoporosis. Keywords: Differentiated thyroid carcinoma, osteoporosis, thyroid-stimulating hormone suppression treatmentItem The role of 18F-FDG PET/CT in the primary staging of Gastric Cancer(Galenos, 2015-12-25) Filik, Mustafa; Kır, Kemal Metin; Aksel, Bülent; Soydal, Çiğdem; Özkan, Elgin; Küçük, Nuriye Özlem; İbiş, Erkan; Akgül, Hikmet; Tıp FakültesiItem The Role of 18F-Flourodeoxyglucose (18F-FDG) Positron Emission Tomography/Computed Tomography (PET/CT) in Pelvic and Paraaortic Lymph Node Staging of Uterine Cervical Cance(Cosmos Scholars, 2014-08-12) Soydal, Çiğdem; İbiş, Erkan; Ortaç, Fırat; Özkan, Elgin; Küçük, Nuriye Özlem; Kır, Kemal Metin; Tıp Fakültesi